
The Science That Raises The Bar
REBALANCING THE SCALP MICROBIOME
Welcome to the science of beautiful, healthy hair. At CULISE, we fuse Korean innovation with advanced microbiome research to create formulas that restore harmony at the scalp level—where true hair transformation begins.
ScalpBiome is the first scalp care microbiome ingredient, directly built from microbiome big data and applied to a product.
Scalp pH Balance
Our formulas maintain an ideal pH range to protect the scalp’s acid mantle, reducing irritation and bacterial imbalance.


Scalp Elasticity
A flexible scalp supports better circulation and nutrient delivery.
Our formulas restore elasticity using microbiome-balancing ingredients.
Microbiome Diversity is Power
A diverse microbiome is a strong microbiome.
Probiotic-infused complexes support balance, protect against irritation, and keep your scalp environment thriving long-term.


Reinforcing Keratin Structure
Keratin is the backbone of strong, silky hair.
Our actives penetrate deep to reinforce keratin from within - reducing breakage, boosting shine, and restoring smoothness strand by strand.
In a 4-week consumer perception study
CLINICALLY PROVEN RESULTS
- 95% reported improved scalp hydration
- 92% noticed less flaking and irritation
- 89% felt stronger, shinier hair
COMMON QUESTIONS
What is the scalp microbiome?
The scalp microbiome is a community of beneficial microorganisms that protect your skin barrier and support healthy hair growth.
Why does pH matter for my scalp?
An optimal pH (4.5–5.5) keeps your scalp healthy by preventing irritation, dryness, and imbalance.
Can I use these products on color-treated hair?
Absolutely. All CULISE formulas are color-safe and enhance color vibrancy over time.
Ready to feel the difference?
Experience the power of our Deep Hydrating Collection.